Scientists have grown up a "hybrid teeth"
People may in future be able to have missing or diseased teeth replaced with ones grown from cells taken from their own mouth, scientists have predicted.
Hybrid teeth created by combining human gum cells and stem cells from mouse teeth have been grown in laboratory mice by researchers who hope the work could lead to dentures being superseded by new teeth grown on a patient's jaw.
The mixture of mouse and human cells was transplanted into adult mouse kidneys and grew into recognisable tooth structures coated in enamel with viable developing roots.
Two kinds of cell were used to make the bioengineered teeth. Epithelial "surface lining" cells were taken from human gum tissue and mesenchymal stem cells from the mouse embryos.
Mesenchymal cells can develop into a range of different tissues, including bone, cartilage and fat.
Previous research has shown that embryonic teeth are capable of developing normally in the adult mouth.